Global Update (non-endemic countries): As of 28 December 2022, 83,582 confirmed cases of mpox
and 282 deaths were reported from 110 countries/territories globally. The countries reporting the
majority of cases are mainly in Europe and the Americas.
Africa update (endemic and non-endemic countries): Since the beginning of 2022, the continent has
reported 1,262 confirmed cases and 226 deaths (CFR: 18%) of mpox from eight endemic Africa Union
(AU) Member States (MS): Benin (3 confirmed cases; 0 confirmed deaths), Cameroon (18; 3), Central
African Republic (CAR) (13; 3), Congo (5; 3), Democratic Republic of Congo (DRC) (319; 204), Ghana
(116; 4), Liberia (4; 0), Nigeria (753; 7) and five non-endemic MS: Egypt (4; 0), Morocco (3; 0),
Mozambique (1; 1), South Africa (5; 0) and Sudan (18; 1). This week, 47 new confirmed cases and
seven new deaths of mpox were reported from CAR and DRC.
Central African Republic: Since the last update (27 May 2022), the MoH reported 5 new confirmed
cases and one new death (CFR: 20%) of mpox. This is a 17% decrease in the number of new confirmed
cases and no percentage change in the number of new confirmed deaths compared to the last brief.
Cumulatively, 13 confirmed cases and three deaths (CFR: 23%) of mpox were reported from six
districts.